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Multimodal, stepwise plans are standard

doi: 10.1093/jnci/djv075 [DOI] [PMC free article] [PubMed] [Google Scholar] 419

Each ten-drop serving of Metabolics Tri B12 liquid delivers 300 g of vitamin B12 (as 100ug of adenosylcobalamin, 100ug methylcobalamin & 100ug hydroxocobalamin), providing ample flexibility for dosing according to individual needs and preferences

Other drugs that are highly extracted by the liver include morphine (see above), isoniazid, propranolol, and several tricyclic antidepressants ( Table 31 )