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Without enough mitochondrial capacity to burn those fatty acids efficiently, they get recirculated and re-deposited, or worse, they overwhelm tissues that cant handle the load (a process called lipotoxicity)

Symptoms typically involve intense cramping and hardening of the muscle, which may last from seconds to several minutes

186 This suggests that targeting USP20 may mitigate chemotherapy resistance and promote ferroptosis in HCC patients, and explains why DNA damage therapy often leads to treatment resistance

Some people are more likely to run low, including: Vegans and vegetarians People with digestive issues (like IBS or coeliac) Older adults Anyone on certain medications People recovering from illness We dont guess