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Ground state destabilization from a positioned general base in the ketosteroid isomerase active site

Apart from its dietary use, it has been extensively used to treat neurological disorders in traditional medicine and has been shown to have anti-diabetic, hepatoprotective, anti-cancer, anti-metastatic, anti-fatigue and vasodilator effects in several experimental studies (19, 20)

Second, although we included recent human randomized controlled trials (e.g., SYNERGIC, DO-HEALTH, PONDER), the findings are mixed

Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation