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Although direct comparison of model predictions to actual concentrations is not feasible when only LLOQ data are available, the developed mother-to-infant model predicted median primaquine concentrations to be below the LLOQ

Encouragingly, multiple Clinical trials are underway or in development aiming to investigate how to improve efficacy and/or limit side effects of CAR T cells, and the world scientific community eagerly awaits their findings

Neuroimaging studies have confirmed that reduced gray matter volume in the dorsolateral prefrontal cortex (DLPFC) of long-term smokers directly correlates with a decline in executive function, whereas compromised cingulum bundle integrity affects emotional regulation [164, 165]