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The World Anti-Doping Agency (WADA) lists IGF-1 and its analogs, including IGF-1 LR3, as prohibited substances

Whether any of these abnormalities are due to abnormal renal tubular expression or function of ATP7B is uncertain

The subjects who received amifostine maintained a normal glomerular filtration rate (GFR), a measure of kidney function, after two chemotherapy cycles, whereas a 30% reduction in GFR occurred in subjects who did not receive amifostine (Hartmann 2000)