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However, once the benzimidazole is detached from cobalt by quaternization with methyl iodide, it is replaced by H 2 O or hydroxyl ions

However, it is possible that in the future some covalent inhibitors may serve as CD38 modifiers in therapies aimed at ex vivo optimization of immune cells therapy for cancer [50]

Immunotherapy with long-lived Anti-CD38 Anti-CD3 bispecific antibodies stimulates potent T cell-mediated killing of human myeloma cell lines and CD38 + cells in monkeys: a potential therapy for multiple myeloma