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Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer

These markers are measurable clinical or biological characteristics that provide insight into a patients likely outcome

doi:10.1161/CIRCULATIONAHA.105.580332 Rooney M, Bottiglieri T, Wasek-Patterson B, et al

By weighing molecular mechanisms against clinical shortfalls, it aims to provide a comprehensive guide to promoting the clinical application of natural products in the treatment of OC