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they evolve as the body adapts

Detection of malondialdehyde (MDA) The level of malondialdehyde, an indicator of lipid peroxidation, was quantified using Lipid Peroxidation MDA Assay Kit (S0131, Beyotime) following the manufacturers instructions

In pathological conditions like ischemia-reperfusion injury, ferroptosis and necroptosis work together in the cellular damage process, regulating the type and extent of cell death (97)