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The costs arising from the regulatory challenges involved in drug repurposing and the unpredictability of the future financial profitability of new clinical trials may deter drug developers from further researching existing drugs [128]

and reviewing manufacturer documentation before commencing laboratory work

Therapeutic hypothermia (TH) is one of them

Given Dihexas potential to promote neural growth and synaptic formation and retention, it presents an intriguing possibility for research in the context of overcoming ALS