glutathione synthetase deficiency genereviews Inborn errors in the metabolism of | Orphanet Journal of Rare Diseases Glutathione Synthetase Deficiency - StoryMD

Conditions like irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), small intestinal bacterial overgrowth (SIBO), and leaky gut syndrome are not only common but often underdiagnosed or mismanaged

Neuropharmacology 56:122132 Carli M, Evenden JL, Robbins TW (1985) Depletion of unilateral striatal dopamine impairs initiation of contralateral actions and not sensory attention

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As GSH has a net negative charge at physiological pH, the high concentration of mGSH implies the existence of specific transport systems that work against an electrochemical gradient (Mari et al., 2009, 2010)