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In animal test models, reported side effects primarily relate to acute systemic vasodilation

Loss of appetite is common, often paired with noticeable weight loss

Studies have shown that thyroid autoimmunity is influenced by genetic variations in adhesion molecules (CD14, CD40), cytokines and their receptors, self-antigens, apoptosis-related gene products, and the promoter region of selenoprotein S (Klubo-Gwiezdzinska And Wartofsky 2022)