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2.3.2 Dysfunction of innate immune cells in MS Innate immune cells within the CNS are key drivers and modulators of damage in MS

However, chronic excessive alcohol consumption leads to significant metabolic disruptions: (1) Disruption of the NADH/NAD + Ratio: This imbalance enhances respiratory chain activity, increases oxygen consumption, and promotes ROS formation (Yang et al., 2022)

Furthermore, larger multi-centric trials with better study designs and larger sample sizes are needed to corroborate the findings of our study

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