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Therefore, Nrf2 establishes distinct routes for controlling other elements of NLRP3 inflammasome-mediated damage to cells, including mitochondria, by interacting with several mediators [88]

The study indicated that the treatment of low dose selenite led to a just marginal increase in GPx activity in NIH3T3, MCF-7, and Sup-T1 cells, whereas identical treatment led to ~ fivefold increase of GPx activity in PC12 and AA8 cells